Research Journal of Pharmacy and Technology

Pseudomonas aeruginosa has one of the broadest ranges of infectivity among all pathogenic organisms. Several pathogenic bacteria are capable of producing extra cellular enzymes that can damage the host tissue directly. These wide range of enzymes serve as virulent factor for those. 20 clinical isolates of P. aeruginosa obtained from different clinical specimens were subjected to antibiotic sensitivity testing and lipase and lecithinase activity. All isolates were uniformly resistant to all antibiotics used with lecithinase and lipase having 95% and 45% resistance respectively. We concluded that our isolates were found to exhibit both lipase and lecithinase activity and this may play a crucial role in causing infections.