1Department of Medicinal Chemistry, Mother Teresa College of Pharmacy, Ghatkesar, R.R. Dist., A.P, India
2Department of Medicinal Chemistry, Nagarjuna University, Guntur, A.P, India
A series of 5-benzylidene-2,4-thiazolidinedione derivatives were synthesized by employing microwave irradiation. The synthesis involves microwave irradiation of an aromatic aldehyde with 2,4-thiazolidinedione in sodium acetate/acetic acid in ethanol. The reaction was completed in 15–30 min with 68–82% yields and was environmentally friendly with easy workup. The synthesized compounds were evaluated for antifungal activity.
