RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY

The study describes a simple and green method for the synthesis of gold nanoparticles using the leaf extract of Caesalpinia bonducella. UV-Vis spectroscopy (UV-Vis), Fourier transforms infrared spectroscopy (FTIR), X-Ray diffraction (XRD) and Transmission electron microscopy (TEM) was used to characterize the gold nanoparticles. FTIR analysis indicates that-OH groups present in the leaf extract were responsible for the reduction of metal cations into nanoparticles. UV-Vis analysis showed a Surface Plasmon Resonance in the range of 518–538 nm due to the formation of gold nanoparticles. XRD studies indicated that the nanoparticles were crystalline in nature with face centred cubic geometry. TEM analysis revealed that the shape of the gold nanoparticles was in spherical forms and the average of particle size was 11±2 nm. In addition, the nanoparticles showed good antimicrobial activity against gram-positive and gram-negative bacterias. Thus, the study emphasizes that the green synthesized AuNPs could be considered as a promising antimicrobial agents.