1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences and Pharmaceutical Industries, Future University in Egypt, Cairo, Egypt
2Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt
This review gives a summary of the stages of schizophrenia, first and second-generation antipsychotics development and the techniques used in their formulations. These methods aim to improve the dissolution of these drugs and hence bioavailability, or to be formulated in controlled release forms, or to improve the brain targeting efficiency.
Schizophrenia, bioavailability