Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2019
  • Volume: 12
  • Issue: 8

Prospective of combination of Marketed and Herbal Resilient mediators in the Management of Diabetes and its related Hepatic Impairment

1Department of Pharmacy, Ponnaiyah Ramajayam Institute of Science and Technology, PRIST University, Vallam, Thanjavur, Tamilnadu, India

2Department of Pharmacy, Dr. D. Y. Patil College of Pharmacy, Pune, Maharashtra, India

Abstract

Diabetes is a metabolic syndrome which covers wide array of organ damage. It mainly causes Diabetic Retinopathy, Neuropathy, Nephropathy Cardiovascular damages, and Hepatic impairment. Diabetic hepatopathy is also an important cause of hospitalizations and mortality. In this study we compared various marketed Antidiabetic combinations by using STZ induced diabetic rats. From herbal Nano Curcumin, Allicin and Supercritical fluid extract of ginger was used in combination with Metformin. Fasting Blood glucose, Lipid characteristics, ALT, AST, ALP Enzyme estimation, HbA1C, and Histopathological sections of liver were studied. In conclusion we can pretend that Ayurveda definitely has answer to diabetic complications.

Keywords

Diabetic Rats, Diabetic Hepatopathy, STZ induced diabetes, Rasayana therapy