Research Journal of Pharmacy and Technology

Myrrha and Sage extract solutions are promising prophylactic and disinfectant agents against microorganisms, suggesting that these solutions might be useful as antimicrobial topical solutions for dental contamination. Three different concentrations of Myrrha and Sage extract solutions 2%, 5% and 10% were separately exposed to the E.coli and chlorohexidine solution that used as control to treat the PMMA and Flexible Acrylic plates, the percentage of colonies reductions were calculated. In case of using Sage extract solutions, the colonies reductions were 82.70%, 90.65% and 94.61% respectively for PMMA plates compared with 97.86% reduction for Chlorohexidine with mean p-value 0.0023, 0.0025, 0.0026 and 0.0009 respectively. As regard Myrrha extract solutions, the colonies reductions for Acrylic flexible plates were 91.75%, 96.15%, 97.08% respectively, compared with 97.91% reduction for Chlorohexidine with mean p-value (0.0017, 0.0010, 0.0005 and 0.0006) respectively. This research considers both Sage and Myrrha and extract solutions of different plants are promising solutions and capable of using them as alternative anti plaque solutions for either PMMA and Flexible Acrylic plates.