1Department of Pharmaceutics, School of Pharmacy, Anurag Group of Institutions, Hyderabad, Pin: 500088, India
2Department of Pharmaceutics, Malla Reddy College of Pharmacy (affiliated to Osmania University), Maisammaguda, Secunderabad, Telangana-500014
3Department of Bioinformatics, Lovely Professional University, Jalandhar, Punjab-144411
Niosomes a novel trend in drug delivery in which medication is encapsulated in a vesicle and the vesicle made up of bilayer of non-ionic surface active agents and then it is named as niosomes. However niosomes are structurally similar to liposomes in having a bilayer, and the materials used to prepare niosomes make them more stable. After preparing the dispersion of niosomes unentrapped drug is separated by gel filtration or centrifugation. A method of invitro release rate study includes the use of dialysis tubing. niosomes are either unilamellar or multilamellar vesicles formed from synthetic non-ionic surfactants. Niosomal drug delivery applicable to many pharmacological agents for their action through various diseases. Hence niosomes have more penetrating capability than the previous preparations of emulsions.
Niosomes, Encapsulation, Surfactants, Vesicles, centrifugation