Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2018
  • Volume: 11
  • Issue: 11

Niosomes: A Novel Trend in Drug Delivery

  • Author:
  • Dibyalochan Mohanty1, M. Jhansi1, Vasudha Bakshi1, Akiful Haque1, S Swapna1, Chinmaya Keshari Sahoo2,, Atul Kumar Upadhyay3
  • Total Page Count: 7
  • Page Number: 5205 to 5211

1Department of Pharmaceutics, School of Pharmacy, Anurag Group of Institutions, Hyderabad, Pin: 500088, India

2Department of Pharmaceutics, Malla Reddy College of Pharmacy (affiliated to Osmania University), Maisammaguda, Secunderabad, Telangana-500014

3Department of Bioinformatics, Lovely Professional University, Jalandhar, Punjab-144411

Abstract

Niosomes a novel trend in drug delivery in which medication is encapsulated in a vesicle and the vesicle made up of bilayer of non-ionic surface active agents and then it is named as niosomes. However niosomes are structurally similar to liposomes in having a bilayer, and the materials used to prepare niosomes make them more stable. After preparing the dispersion of niosomes unentrapped drug is separated by gel filtration or centrifugation. A method of invitro release rate study includes the use of dialysis tubing. niosomes are either unilamellar or multilamellar vesicles formed from synthetic non-ionic surfactants. Niosomal drug delivery applicable to many pharmacological agents for their action through various diseases. Hence niosomes have more penetrating capability than the previous preparations of emulsions.

Keywords

Niosomes, Encapsulation, Surfactants, Vesicles, centrifugation