Research Journal of Pharmacology and Pharmacodynamics

  • Year: 2017
  • Volume: 9
  • Issue: 3

Antipsoriatic Activity of gel containing Methylsulphonylmethane Powder and seed oil of Pongamia pinnata Linn.

1Assistant Professor, LNBC Institute of Pharmacy, Raigaon Satara, Maharashtra, India, 415020

2Associate Professor, Department of Pharmacology, Adarsh College of Pharmacy, Vita Dist Sangli

Abstract

To develop gel using Methylsulphonylmethane powder and seed oil of Pongamia pinnata Linn. to minimize side effects of current therapy. All prepared formulations were evaluated for pH, Viscosity, spradability, Extrudability. The release of optimized batch was carried out using Cellophane membrane into Phosphate buffer 6.8 at 37°C. The Characterization was carried out by using FTIR, DSC, SEM analysis. In-vtro & In-vivo activities were performed by using HaCaT Cell line and Mouse tail model respectively

Keywords

Psoriasis, Orthokeratosis, Pongamia pinnata, Methylsulphonylmethane