Research Journal of Pharmacognosy and Phytochemistry

  • Year: 2018
  • Volume: 10
  • Issue: 3

Pharmacological Studies on Flowers of Ceropegia bulbosa Roxb. var. bulbosa and lushii (Grah.) Hook. F from Thar Desert of Rajasthan, India

2Professor, Department of Botany, Jai Narain Vyas University, Jodhpur (Raj.), India

1Research Scholar, Department of Botany, Jai Narain Vyas University, Jodhpur (Raj.), India

Abstract

Plants synthesize organic compounds continuously to play an important role in maintenance of human health. The characterization of floral chemical constituents of Ceropegia bulbosa Roxb. var. bulbosa and var. lushii was done using GC-MS technique.

Flowers were collected from typical xeric conditions of Indian Thar Desert of Rajasthan, during the month of August-October. The phytochemical compounds were investigated using Perkin-Elmer gas chromatography-mass spectrometry, while the mass spectra of the compounds found in the extract were matched with the National Institute of Standards and Technology (NIST) and Willey 2008 library.

Maximum % area is found for 24-Norursa-3, 12-diene, is present in maximum amount (41.94%) with retention time (RT) =43.658 minutes, followed by Hexadecanoic acid, 2-hydroxy-1(hydroxymethyl) ethyl ester (8.72%) with RT=28.029 minutes in the methanolic extract. Pentacosane is present in maximum amount (39.52%) with retention time (RT)=26.585 minutes, followed by Tetracontane (34.28%) with RT=28.656 minutes in the chloroform extract of flowers of Ceropegia bulbosa Roxb. var. bulbosa. Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl) ethyl ester is present in maximum amount (26.25%) with retention time (RT) =28.039 minutes, followed by Octadecanoic acid, 2, 3-dihydroxypropyl ester (12.39%) with RT=30.181 minutes in the methanolic extract. Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl) ethyl ester is present in maximum amount (40.39%) with retention time (RT)=28.139 minutes, followed by Octadecanoic acid, 2, 3-dihydroxypropyl ester (24.49%) with RT=30.237 minutes in the chloroform extract of flowers of Ceropegia bulbosa Roxb. var. lushii.

The floral extract of Ceropegia species using methanol and chloroform as a solvent could isolate individual components from mass spectra of the constituents. The isolated bioactive floral phytocomponents of this plant could play an important role in development of new medicine and noval drugs to prevent and treat various diseases or aliments.

Keywords

Asclepiadaceae, Ceropegia species, Chloroform, GC-MS, Medicinal plants, Methanol, Phytochemical constituents, Secondary metabolites