Research Journal of Pharmaceutical Dosage Forms and Technology

Nanoemulsion was described as a promising delivery system for various drugs, including biopharmaceuticals. Nanoemulsion is a heterogeneous network consisting of one immiscible liquid that was distributed within another liquid as droplets. This study aimed to investigate the nanoemulgel as a transdermal delivery system for a drug that is poorly water-soluble. Different components of nanoemulsion (oil, surfactant, and cosurfactant) were selected based on the solubility and emulsification capacity. A high-pressure Homogenization technique was used for Nanoemulsion preparation. The gelling agent was applied to transform nanoemulsion to nanoemulgel as a gel matrix. Nanoemulgels loaded with drugs were characterized for particle size, SEM, viscosity, spreadability, extrudability, pH, Stability.