1Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, 010018, Inner Mongolia, P.R. China
2Camel Research Institute of Inner Mongolia, Alxa, 737300, Inner Mongolia, P.R. China
The composition of camel milk includes antioxidants that are beneficial for liver function and regulate gene expression. Here we evaluated the protective effects of camel milk in mice. Our results revealed that camel milk protected the liver by decreasing levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and malondialdehyde (MDA), and increasing the activity of superoxide dismutase (SOD) and glutathione (GSH) in mice. Histopathological examination demonstrated that the livers of mice receiving camel milk were not different to those of control mice. The mRNA expression of SAA1, TGF-α, TNF-α, and LCN2 was down-regulated in the livers of mice receiving camel milk. These results indicate that camel milk significantly increases the antioxidant capability of the liver and regulates gene expression in mice. Thus it is opined that regular consumption of camel milk has hepato-protective effect.
Camel milk, Hepatoprotective, Antioxidant activity, Regulating gene expression
