Biotech Today

  • Year: 2020
  • Volume: 10
  • Issue: 1

Bioproduction of Lactic Acid Exposed to Metronidazole

  • Author:
  • Shivankari1, Shalini Singh2, S. P. Singh1,*
  • Total Page Count: 3
  • Published Online: Dec 16, 2020
  • Page Number: 43 to 45

1Department of Chemistry, Magadh University, Bodh-Gaya

2Department of Chemistry, Govt. Autonomous Model Science College, Bilaspur, (C.G.)

Abstract

The efficacy of metronidazole on bioproduction of lactic acid by some lactic acid producing bacteria such as Lactobacillus jugrti NCIM- 2367, Lactobacillus lactis NCIM-2369, Lactobacillus plantarum NCIM-2373, Lactobacillus brevis NCIM-2436 and Lactobacillus delbrueckii NCIM-2025 has been studied. The bacterial strain Lactobacillus delbrueckii NCIM-2025 has been found quite effective and useful for maximum bioproduction of lactic acid, i.e,; 11.253 g/100 ml of lactic acid which is 17.096% higher in comparison to control fermentor flasks, i.e,; 9.610 g/100ml at 7.0×10 M molar concentration of metronidazole mutagene. It has been found that bioproduction of lactic acid in the presence of metronidazole at optimum molar concentration, i.e; at 7.0×10 M attains its best activity when 24% (w/v) molasses solution is allowed to ferment for 5 days of optimum incubation period, at 38°C temperature by maintaining the pH value of the fermentation medium at 5.9 along with other nutritional ingredients required by the lactic acid bacteria.

Keywords

Lactic acid fermentation, Metronidazole, Molasses, Lactobacillus delbrueckii NCIM-2025, pH, Temperature and incubation period.