1Department of Chemistry, Dinakrushna College, Jaleswar, Balasore-756084, Odisha, India
2Department of Chemistry, Utkal University, Bhubaneswar-751004, Odisha, India
Chemical synthesis of bioactive compounds from natural sources is a part and parcel of drug discovery and development process. Developing new synthetic strategies and methods towards such compounds is therefore an attractive option for obtaining larger quantities of the natural product without putting strain on the natural resources. Designing synthetic routes for convergent and viable synthesis from readily available materials is very fundamental to natural product synthesis. In this paper, we endeavor to profile some synthesis schemes for a natural pyrazole alkaloid ‘Withasomnine’ in a novel way basing on Synthon Disconnection Approach.
Bioactive, natural product, synthesis, Synthon disconnection approach, withasomnine
