Asian Journal of Research in Chemistry

The condensed reaction of aromatic ketone, 5-Chloro-2-hydroxy-4-methyl-acetophenone with aniline and its derivatives each separately viz. Aniline, 4-Amino-phenol, 2-Amino-thiophenol, 4-Amino-thiophenol, 4-Chloro-2-nitro-aniline, 2-Amino-benzonitrile and 4-Amino-benzonitrile and reacted efficiently to produced a series of ketimines in high yield and purity. These were analyzed by employing the TLC technique. All the products were characterized by their colour, physical constant, TLC, elemental analysis and spectral(UV-Vis and FTIR) method. After confirming their desired molecular studies, these ketimines were studied for their antifungal activity using A. alternata, and F. oxysporum.