Asian Journal of Research in Chemistry

5-bromo 2, 3-diamino pyridine and ethylpyruvate react each other to form 7-bromo-2-methylpyrido[2, 3b]pyrazin-3-ol (1) which further reacts with ethylchloroacetate and formethyl 2-((7-bromo-2-methylpyrido[2, 3b]pyrazin-3-yl)oxy)acetate (2). Compound 2 on reaction with hydrazinehydrate gives 2-((7-bromo-2methylpyrido[2, 3-b]pyrazin-3-yl)oxy)acetohydrazide (3), which on condensation with different aldehydes produce N’-Arylidene-2-((7-bromo-2-methylpyrido[2, 3-b]pyrazin-3-yl)oxy)acetohydrazides (4a-e).