1Dept of Pharmaceutical Chemistry, SND College of Pharmacy, Bhabhulgaon, Yeola
2Dept of Quality Assurance, Mahatma Gandhi Vidyamandir’s Pharmacy College, Nashik
Isoniazid is an organic compound. It is a first line drug used in prevention and treatment of tuberculosis also Isoniazid has an anti-depressant effect. Isonicotin hydrazine is also known as isoniazid. A process was developed for the preparation of isoniazid from citric acid via citrazinic acid 2, 6-dichloroisonicotinic acid, isonicotinic acid and ethyl isonicotinate. Yields and procedures in all steps were improved (1).
Isoniazid, Citrazinic acid, Isonicotin, Anti-depressant, Tuberculosis
