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Research Journal of Pharmacy and Technology
Year : 2014, Volume : 7, Issue : 9
First page : ( 1014) Last page : ( 1019)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.

Analgesic and Antipyretic Effects of Ficus dalhouseae Miq. Leaf Ethanolic Extract

Ghori Syed Safiullah1,3,*, Khan Mohib2, Qureshi Mohammed Shamim3, Ghori Syed Kaleemullah3

1Research Scholar, Department of Pharmacology, Himalayan University, Naharlagun, Itanagar, Arunachal Pradesh

2Department of Pharmacognosy and Phytochemistry, Oriental College of Pharmacy, Sector2, Plot 3,4,5 Sanpada (E), Navi Mumbai

3Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad-500001, Andhra Pradesh, India

*Corresponding Author E-mail: safiullahghori@gmail.com

Online published on 22 October, 2014.

Abstract

The ethanolic extract of Ficus dalhousiae Miq. was studied for its Analgesic and Antipyretic effects in Wister albino mice and rats. The plant material after collection and drying was extracted by soxhlation process. Analgesic activity was performed in albino mice and antipyretic activity was done in albino rats Hot Plate and Acetic acid induced writhing methods were used for assessment of analgesic activity. Yeast induced pyrexia model was used for determination of antipyretic activity. The Ethanolic Extract of leaves of Ficus dalhousiae Miq. at the dose of (250mg/kg and 500mg/kg) produced a dose dependent significant analgesic effect both in hotplate and acetic acid induced method(P <0.001). However the extract at the same doses as above showed weak antipyretic effect (P <0.01)when compared with the control group.

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Keywords

Ficus dalhousiae Miq, Analgesic, Antipyretic.

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