Synthesis and Biological Activities of Some Novel Heterocyclic Compounds Containing Thiazolidinone Derivatives Puttaraj C., Bhalgat Chetan M., Chitale Sandeep K., Ramesh B.* Department of Pharmaceutical Chemistry, S.A.C. College of Pharmacy, B.G.Nagara-571448, Mandya *Corresponding Author E-mail: rambha_vin@yahoo.com
Online published on 3 April, 2013. Abstract Amino group of thiazole moiety have been treated with various aromatic aldehydes gave corresponding Schiff's bases, 3A-G. These Schiff's bases have been reacted with thioglycolic acid, anhydrous zinc chloride and N,N�-dimethyl Formamide as a solvent to get corresponding novel thiazolidinone derivatives, 4A-G. Structures of all the newly synthesized compounds were confirmed by IR, 1H NMR, and mass spectral data. The synthesized compounds were evaluated for their antioxidant activity. Few compounds were found with potent antioxidant activity. Top Keywords Thiazole, Thiazolidinone, Sciff's bases, Antioxidant activity. Top |