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Evaluation of (In-Vitro) Anti-Inflammatory Activity of Azomethines of Aryl Thiazoles Niraimathi V*, Jerad Suresh A, Kokil A.R. Department of Pharmaceutical Chemistry, College of Pharmacy, Madras Medical College, Chennai –3 *Corresponding Author E-mail: vnm_anr@yahoo.co.in
Online published on 3 April, 2013. Abstract The anti-inflammatory activity of azomethines of aryl thiazoles synthesised was evaluated by in-vitro membrane stabilisation study. The effect on inflammatory condition was studied on erythrocytes exposed to hypotonic solution. The anti-inflammatory activity was compared with diclofenac sodium as reference standard against the in-vitro model. Results of the evaluation revealed that the synthesised compounds exhibited membrane stabilising action leading to anti-inflammatory activity. Top Keywords Azomethines, Thiazoles, Anti-inflammatory activity, membrane stabilising activity. Top | |
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