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Wound Healing Activity of Hydroalcoholic Extract of Acacia catechu Karwani Gauri*, Singhvi I. J., Gupta S.K., Agarwal A. Pacific College of Pharmacy, Udaipur, Rajasthan, India, 313 002 *Corresponding Author E-mail: grkarwani@gmail.com
Online published on 3 April, 2013. Abstract The entire wound healing process is a complex series of events that begins at the moment of injury and can continue for months to years. The stages of wound healing are inflammatory phase, proliferation phase, fibroblastic phase and maturation phase. The hydroalcoholic extract of Acacia catechu (400 mg/kg/day) was evaluated for its wound healing activity in albino rats using excision and incision wound models. Extract treated animal's exhibit significant reduction in wound area when compared to controls. The extract treated wounds are found to epithelize faster as compared to controls. Extremely significant (p<0.0001) increase in granuloma breaking strength (430.85±10.64) was observed. The betadin ointment 15% was used as standard. Top Keywords Acacia catechu, Wound healing, Excision wound, Incision wound, Betadin ointment 15%. Top | |
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