Laxative and Anthelmintic Potential of Cassia alata Flower Extract Adnaik R.S., Bhagwat D.A., Raut I.D., Mohite S.K., Magdum C.S. Department of Pharmacology, Rajarambapu College of Pharmacy, Kasegaon, Tal. Walwa, Dist. Sangli 415 404, Maharashtra, India *Corresponding Author E-mail: rahul.cology@gmail.com
Online published on 3 April, 2013. Abstract The present study was undertaken to screen the laxative and anthelmintic activity of Cassia alata flowers. The laxative activity was performed at a dose of 100 mg/kg and 200 mg/kg according to Cappaso et al in albino rats. Anthelmintic activity was evaluated separately on adult Indian earthworms, Pheritima posthuma by the method of Nargund. Agaragar and piperazine citrate were used a standard drugs for laxative and anthelmintic activity respectively. The flower extract was found to produce significant (p>0.05) and dose-dependent increase in fecal output showing laxative activity; the 200 mg/kg dose being more potent. The extract was also found to paralyze and cause death of worms; showing significant anthelmintic activity. Top Keywords Laxative, Pheretima posthuma, Cassia alata Linn, agar-agar. Top |