Formulation and evaluation of polyherbal gel Baitule A. W.1,*, Tawar M. G.2, Pande S. D.3 1Associate Professor, Vidyabharati College of Pharmacy, Amravati, India 3Principal, Vidyabharati College of Pharmacy, Amravati 2Principal P. R. Pote Patil College of Pharmacy, Amravati *Corresponding Author E-mail: prof.ajaybaitule@gmail.com
Online Published on 13 October, 2023. Abstract The present study has been undertaken with the aim to formulate and evaluate the new polyherbal gel formulation containing hydroalcoholic extract from Trigonella foenum-graecum and Glycyrrhiza glabra. The polyherbal gel formulation was designed by using Carbopol 934, Sodium CMC, Trigonella foenum-graecum, Glycyrrhiza glabra extract, ethanol, propylene glycol 400, methyl paraben, propyl paraben, and required amount of distilled water. The skin ph (6.8-7) was maintained by drop wise addition of tri- ethanolamine. The prepared gels were evaluated for physical appearance, pH, spreadability, HPTLC, skin irritation to observe side effect. It was inferred from the results that polyherbal gel formulations were good in appearance and homogeneity. The values of spreadability indicated that these polyherbal gels were easily spreadable by small amount of shear. Viscosity of polyherbal gels were determined by using Brookfield viscometer. Formulation F4 had good values of spreadability, viscosity, pH and during the accelerated stability studies the appearance was clear and no significant variation in spreadability and pH was observed. Hence 0.3 % hydroalcoholic extract from Trigonella foenum-graecum and Glycyrrhiza glabra gel was formulated . F4 formulation and its physiochemical study was found to be good. Top Keywords Carbopol 934, Sodium CMC , Trigonella foenum-graecum, Glycyrrhiza glabra, HPTLC. Top |