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Research Journal of Pharmacy and Technology
Year : 2023, Volume : 16, Issue : 4
First page : ( 1869) Last page : ( 1874)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2023.00306

Formulation of peel-off gel mask from of carbopol (Daucus carota L) Skin extract as antioxidant with variations of carbopoly base 940 and propylene glycol

Yuliani Ni Nyoman1, Siswandono2,*, Erawati Tristiana2, Sambara Jefrin1, Blegur Fatmawati1, Poddar Sandeep3

1Department of Pharmacy, Ministry of Health Poltekkkes Kupang, Jl. Piet A. Tallo, Liliba, Kec. Oebobo, Kota Kupang, Nusa TenggaraTim., Indonesia

2Faculty of Pharmacy, Airlangga University, Jl. Airlangga No.4 - 6, Airlangga, Kec. Gubeng, Kota SBY, Jawa Timur60115, Indonesia

3Deputy Vice Chancellor (Research & Innovation) Lincoln University College, Wisma Lincoln, 12-18, Jalan SS 6/12, 47301Petaling Jaya, Selangor D. E., Malaysia

*Corresponding Author E-mail: prof.sis@ff.unair.ac.id

Online Published on 13 October, 2023.

Abstract

Antioxidant compounds reduce ageing of the skin. Carrot peels contain antioxidant compounds. This research aimed to determine whether the red dragon fruit peels can be made into preparations like peel-off mask gel with variations in carbopol 940 and propylene glikol as the influence of variations in the physical basis of the quality of preparation and antioxidant activity. Carrot peel extraxtion by a maseration method using 70% ethanol. Peel-off mask gel made with a variable concentration of carbopol 940 and propylene glycol which is 0.5%: 5%; 0.5%: 7.5%; 0.5%: 10%; 1%: 5%; 1%: 7.5%; and 1%: 10%. The DPPH (1,1-dyphenil-2-picrylhydrazyl) method was used for the antioxidant test. The evaluation is used for observing the physical properties, which include organoleptic, time to dry, viscosity, spreading, and pH, with antioxidant activity of each formula. The results showed that the carrot peels can be made into a prepared peel-off mask gel. The low amount of propylene glycol and high amount of carbopol 940 affected the quality of the preparation. It had a high viscosity, low dispersive power, an acid pH, dried out slowly, and had low antioxidant activity.

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Keywords

Carrot peels, Carbopol 940, Propylene glycol, Peel-off mask gel.

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