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Research Journal of Pharmacy and Technology
Year : 2023, Volume : 16, Issue : 4
First page : ( 1679) Last page : ( 1684)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2023.00275

Guidelines and protocol of managing patients with breast problems during pregnancy and lactation

Gado Amira1,*, Ahmed El-Minawi1, Razek Naaglaa Abdel2, Louis Mariam Raafat2, Osman Omneya M.1

1Department of Obstetrics and Gynecology, Kasr Al-Ainy Faculty of Medicine, Cairo University, Cairo, Egypt

2Department of Radiology, Kasr Al-Ainy Faculty of Medicine, Cairo University, Cairo, Egypt

*Corresponding Author E-mail: gadomira228@gmail.com

Online Published on 13 October, 2023.

Abstract

Most of the breast lesions found during pregnancy are benign. Pregnancy associated breast cancer (PABC) is defined as cancer that occurs during pregnancy or within 1 year of delivery.

Aim of The Study

To diagnose breast lesions during pregnancy, detect incidenceof masses as well as the incidence and early diagnosis of PABC.

Patients and Methods

500 pregnant women (190 primigravida, 254 mutigravidaand 56 lactating) attending Kasr Al Ainy outpatient clinic having breast complaints were included in the study. Ultrasound was performed for all patients. Further investigations were performed when indicated (Mammography, MRI or core biopsy).

Results

Incidence of breast mass was 25.6%. Within those cases, 5.46 had PABC. The overall incidence of PABC was 1.4%. Biopsy was performed in 13 patients (9 pregnant and 4lactating). We diagnosed 7 malignant masses (4 lactating and 3 pregnant). Pathology revealed5 invasive duct carcinoma, 1 inflammatory carcinoma and 1 adenocarcinoma. Positive family historywas found in 85.7% of malignant cases.

Conclusion

Most breast masses were benign. The overall incidence of PABC was 1.4% and 5.46% within patients diagnosed with a breast mass. Obstetricians should be aware of the importance of breast examination when there is a breast complaint during pregnancy.

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Keywords

PABC, Breast Ultrasound, Mammography, MRI, Core biopsy.

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