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Research Journal of Pharmacy and Technology
Year : 2022, Volume : 15, Issue : 1
First page : ( 188) Last page : ( 192)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2022.00030

Screening of novel hybrid combinations of synthetic drugs with plant extracts for its In vitro antioxidant activity

Savant Chetan1,*, Kulkarni Venkatrao1, Habbu Prasanna2, Kulkarni Preeti1, Majeed Muhammed3, Nayak Mahadeva3

1Department of Pharmacology, SET's College of Pharmacy, Dharwad-580002, Karnataka, India

2Department of Pharmacognosy, SET's College of Pharmacy, Dharwad- 580002, Karnataka, India

3SAMI Labs Limited, R&D Peenya Industrial Area, Bengaluru- 560058, Karnataka, India

*Corresponding Author E-mail: chetan.savant@yahoo.com

Online Published on 13 June, 2022.

Abstract

The present experiment was carried out with the aim to screen selected herb-drug for its antioxidant activity in combination and individually. The antioxidant activity of test samples were estimated by 2,2 Diphenyl -1-picryl hydrazyl (DPPH) radical scavenging activity, hydroxyl radical scavenging activity, reducing power assay. All the selected herb-drug combinations have shown significant antioxidant activity in all three antioxidant procedures compared to individual herb or drug sample. Hence, it may be concluded that herb-drug combinations have better antioxidant potential than alone.

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Keywords

Tinospora cordifolia, Ocimum sanctum, Terminalia arjuna, Antioxidant activity, Atenolol, Propranolol and Amlodipine.

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