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Research Journal of Pharmacy and Technology
Year 2021, Volume-14, Issue-6 (June)
Print ISSN : 0974-3618
Online ISSN : 0974-360X

Table of contents

Research Article

In-vitro comparative study on blood clotting time of some plants extracts and heparin when infected with snakebite
Khalid Abdulkareem Mohammad

Isolation and identification of two triterpenoids from ethyl acetate extract of bark of Boehmeria rugulosa
Abha Shukla, Anchal Choudhary, Rishi Kumar Shukla, Amanpreet Kaur

Optimization of growth medium and physicochemical parameters for high-yield biomass production and active metabolites from Aspergillus terreus
P.B. Rajitha, Prashantha Naik

Anticalculi activities of apigenin hot melt extrusion results with soluplus® and kollidon® va 64 polymers on wistar rats
Sofi N. Stiani, Anas Subarnas, Taofik Rusdiana

Rapid, sensitive and simple lc-ms/ms method development and validation for estimation of phenytoin in human plasma by using deuterated internal standard
Dr. Ajay I. Patel, Kishna Ram, Ms. Swati Guttikar, Dr. Amit Kumar J. Vyas, Dr. Ashok B. Patel, Dr. Nilesh K. Patel, Dr. Vikash Trivedi

A randomized comparative trial to study the effect of preoperative single shot epidural with ropivacaine in lumbar laminectomy
Dr. Karuna Taksande, Dr. G. Swathi Reddy

Microscopic and phytochemical analysis of Desmodium velutinum (willd) DC and Desmodium gangeticum (L.) DC. Panchanga powder
Jigyasa Pathak, M. P. Aswathi, B. R. Patel, C. R. Harisha, Shukla J. Vinay

Knowledge and attitude towards basic life support (BLS) among dental students of dental colleges in South India
Vignesh Kamath, B V Swapna, Smitha Sammith Shetty, Priya Mukherjee, Anoop Mayya, Liang Kai Yuan

The high necessity of rapid antigen detection test (radt) use to guide antibiotic prescribing pattern for acute pharyngotonsillitis in Syria
Hussam Zein Al-Abedine, Afraa Zrieki

Development and validation of uv-visible spectrophotometric method for the estimation of curcumin and tetrahydrocurcumin in simulated intestinal fluid
Jai Bharti Sharma, Sherry, Shailendra Bhatt, Vipin Saini, Manish Kumar

Design and characterization of orlistat bilayered controlled release tablets
P. V. Kamala Kumari, Y. Srinivasa Rao, S. Akhila, K. Bhavya Sindhu

Evaluation of the bacteriological risk of solid medical and pharmaceutical waste from a moroccan hospital center
Oussama Chauiyakh, Aziz Et-tahir, Kamal Kettani, Abdelaziz Chaouch, Halima Bessi

Exploration its antioxidant and immunogenic potential of protein: Calendula officinalis and Dianthus chinensis
Abhishekh Tripathi, Shubham Tyagi, Gurpreet Singh, Karishma Ghosh, Dr. Amit Gupta

Detection of p-lactamase in clinical samples of Prakasam district, Andhra Pradesh
Dasari Venkateswarlu, Arjun Pandian, Samiraj Ramesh

The effect of eucalyptol on sod and il-10 expression in mice exposed to methyl methacrylate vapor
Sianiwati Goenharto, Elly Rusdiana, Sherman Salim, I. Ketut Sudiana

Study the gold compound (aucu) in kcl using cyclic voltammetry by nano sensor
Ahmed A. Mohsin, Muhammed M. Radhi, Wisam H. Hoidy

Rp-hplc method for determination of gemfibrozil using central composite design (CCD)
Dr. Ajay I. Patel, Krupa B. Prajapati, Ms. Swati H. Jolapara, Dr. Amitkumar J. Vyas, Dr. Ashok B. Patel, Dr. Nilesh K. Patel, Ms. Minakshi M. Pandey

Pharmacognostical and physico-chemical evaluation of Ativishadi churna - an ayurvedic formulation
Chandanpreet Singh Sidhu, Saurabh Singh, Dileep Singh Baghel, Sachin Kumar Singh, Bimlesh Kumar, Monica Gulati, Narendra Kumar Pandey, Sheetu Wadhwa, Iqbaljeet Kaur, Hetal Aghera

Effect of ultrasound and calf stretching in relieving gastrocnemius tightness in subjects with plantar fascitis
Dr. M V Sowmya, S. Nandhini, V. Manigandan

Design, molecular docking, synthesis and biological evaluation of 5, 7 dimethyl pyrido(2, 3-D) pyrimidin-4-one and 4,5 dihydro pyrazolo (3, 4-D) pyrimidines for cytotoxic activity
M. Sathish Kumar, M. Vijey Aanandhi

Synthesis and characterization of new poly p-lactam from poly acrolein and study corrosion inhibition for stainless steel in hydrochloric acid solution
Amaal S. Sadiq, Entesar O. Al-Tamimi

Comparative In-vivo study of laxative, anti-diarrheoal and anti-emetic activity of ethanolic and ethyl acetate leaf extract of Citrus limon in rats and chicks
K. Ravishankar, K. Sudharani

In-vitro cytotoxicity, antimicrobial activities and dna binding studies, of novel copper (II) complex with heterocyclic base
V. Shalini, R. Deepika, M. N. Arumugham

Generation of neurodegenerative phenotype using Drosophila melanogaster through paraquat treatment and an amelioration by Tinospora cordifolia (giloy)
Mahendra P. Singh, Twinkle, Ranjana Himalian

Determination of ocular irritancy potential of ophthalmic products using het-cam method
Anand K. Babu, Ram R. Narayanan

Catechism of protective potential of areca catechu in isoprenaline challenged wistar rats
Abdullah Ansari, Tarique Mahmood, Paramdeep Bagga, Farogh Ahsan, Arshiya Shamim, Shoaib Ahmad, Mohammad Shariq, Saba Parveen

A combination approach using areca nut and ketoconazole for treating cutaneous candidiasis
Manoj M. Wagle, Kiran Noel Lobo, Rajath R. Kanchan, Adithya Chandrashekar, V.M. Subrahmanyam

The effects of brotowali (Tinospora crispa) extract on the number of macrophage cells in wistar rats (Rattus norvegicus) suffering from periodontitis
Tuti Kusumaningsih, Ira Arundina, Tantiana, Rini R. Devijanti, Indeswati Diyatri, Mohammed Aljunaid, Poppy Raissa Hudayanti

Physical and chemical methods of extraction of bioactive molecules from Lepidium sativum linn. and antioxidant activity-based screening and selection of extracts-probable phytochemical, chromatography and mass spectroscopy analysis-based correlates
R. Rajasekaran, P. K. Suresh

Uv detection and avoidance of protein in Basella alba leaf mucilage polysaccharide by differential precipitation
P. Arvind, S. Priyadarshini, B. Duraiswamy, S.P. Dhanabal, G. Ramu

Formulation and characterization of eplerenone mucoadhesive buccal tablets
Harini Amballa, Navaneetha Kaluva, Sree Giri Prasad Beri, Krishna Mohan Chinnala, Mayuri Konda

Synthesis, characterization and biological evaluation of some novel2-substituted aminothiazoles
Suresh Kumar, Renu Saharan, Randhir Singh

Acute and sub-acute toxicity study of amrtadi churna
Sangeeta Mukhi, Anindya Bose, Dilip Kumar Das, Sitansu Kumar Panda, Debahuti Mohapatra, S. Latha, Ashok Kumar Balaraman

Phytochemical screening, In-vitro antioxidant and cytotoxic potentials of Brachychiton rupestris leaves
Heba R. Mohamed, El-Sayed S. Abdel-Hameed, Eman A. El-Wakil, Maher M. El-Hashash, Mohamed Shemis

Stability indicating simultaneous estimation of phenylephrine hcl and bromhexine hcl in combined tablet dosage form by uv-spectrophotometer
T. M. Kalyankar, S. J. Wadher, M. R. Bodhankar, Mustasin F. Sayed

Incidence of infant death among the baiga tribe of Chhattisgarh, India
Jitendra Kumar Premi

Method development and validation of propofol by reverse phase hplc and its estimation in commercial formulation
Kuntal Mukherjee, S. T. Narenderan, B. Babu, Survi Mishra, S. N. Meyyanathan

Potential antiseptic of Rhodomyrtus tomentosa leaves extract on healing wound in male wistar rats
Endang Sri Purwanti Ningsih, Noorlaila, Muhammad Ikhwan Rizki, Windy Yuliana Budianto

Antihyperglycemic activity of Typha elephantina leaves using In vivo and in vitro techniques
Supriya Agnihotri, Gurvirender Singh, Santosh Kumar Verma

Co-administration of ondansetron with tramadol decreases efficacy of tramadol in intensive care unit patients
Dr. Nikhil Bhalerao, Dr. Amol Singam

Formulation and evaluation of mouth dissolving tablet of benazepril hydrochloride
Vani H. Bhargava, Poonam S. Sable, Deepak A. Kulkarni, Geeta P. Darekar

Clec4e as a new tumor marker for early diagnosis of git tumors
Rasha Hasan Jasim, Hadeer Haider Abdualameer

Evaluation of anti-hyperuricemic activity of the alcoholic extract of dried Capparis moonii wight fruits in wistar rats
Ms. Shruti Ramesh Shettigar, Dr. (Mrs.) Vanita G. Kanase

Q-absorbance ratio spectrophotometric method for the simultaneous estimation of metformin hydrochloride and voglibose in tablet dosage form
Kedar R. Tejashree, A.R. Dashetwar, D.P. Kardile, A.P. Jadhav, V.C. Bhagat, R.V. Shete

Histopathological and hormonal evaluation of interaction effects of ethidium bromide, Nigella sativa, and silver nanoparticle on male rat fertility
Ali M. Ethaeb, Sattar J.J. Al-Shaeli, Tamarah H. Ahmed

Role of the hospital pharmacist in the quality of gastroenterology endoscopy care
Mohamed Reda Sefrioui, Jaouad Akrim, Hicham Fettah, Wissale Elammani, Sanaa Derfoufi, Adnane Benmoussa, Soufiane Derraji

Phytochemical isolation and anti-inflammatory properties of various extracts of Lilium polyphyllum
M. Amin Mir, Muhammad Waqar Ashraf, Priya Singh

Formulation and evaluation of triclosan dispersible tablets for oral hygiene
Konda Mayuri, Kukkdapu Pavan Kumar, Neela Swapna, Chinnala Krishna Mohan

Comparative evaluation of microleakage of two step etch and rinse, two step self etch and universal dentin bonding
Mohammad Reza Soltani, Nasim Dadfar, Kiana Ghannadan

Review Article

A role of clinical trial in management of hypertension and medication of hypertension
Patel Minesh, G.S. Chakraborthy

Development and validation of hplc determination of related substances in a novel anticonvulsant agent epimidin
Hanna I. Severina, Svitlana M. Gubar, Ivan V. Bezruk, Anna S. Materiienko, Liudas Ivanauskas, Vera A. Bunyatyan, Sergiy M. Kovalenko, Olha O. Scupa, Victoriya A. Georgiyants

Medical students’ preference, attitude and perception toward basic medical science subjects in a Public University, East Malaysia
Tin Moe Nwe, Belinda Anak Nojeb, Jeremy Hoo Ting Wang, Mathilda Frances Anak Julius, Nurul Izzah Mawaddah Mohamad Johar, Swe Swe Latt, Khin Than Yee, Soe Lwin

Development and validation of uplc-ms/ms method for the determination of rivaroxaban in human plasma using liquid-liquid extraction
Kailash Chander Malik, Manoj Karwa, Gaurav K. Jain, Rohit Dutt

Preparation of anti-immunodeficiency pills by the herbal solution
G.V. Aatral, S. Samraj, S. Kavitha, N. Arunkumar, E. Nakkeeran, G. Surendran

Determination of Candida albicans fungus proteins concentration by elisa method at intramuscular introduction in candidiasis therapy
Mykola Rybalkin, Tatiana Diadiun, Natalia Khokhlenkova, Yuliia Azarenko, Serhiy Stepanenko

N-(chlorobenzyl) formamide as an antituberculosis agent from multicomponent reaction synthesis
Desy Ayu Irma Permatasari, Ritmaleni, Titik Nuryastuti

Uv spectrophotometric method development and validation of darunavir in bulk and solid dosage form
Dr. Varsha Tegeli, Avinash Birajdar, Vinod Matole

Root canal morphology of maxillary second premolars for patients attending ajman university
Musab Hamed Saeed, Karrar Mohammed Hassan Hadi, Sarmad Basil Al-Chalabi, Zaid Mohammed Hassan Hadi, Mawada Hassan

The effect of body mass index on health-related parameters in university students
Muhammad Zuhaili Suhaimi, Rabiu Muazu Musa, Muhammad Zulhusni Suhaimi, Mohamad Razali Abdullah, Ahmad Bisyri Husin Musawi Maliki

Direct spectrophotometric determination of perindopril erbumine and enalapril maleate in pure and pharmaceutical dosage forms using bromocresol green
Amir Alhaj Sakur, Bayan Balid

The effect of sulphated cellulose on system of haemostasis
Nozim N. Khoshimov, Guli M. Raimova, Kabul E. Nasirov, Zulayho A. Mamatova, Nodira I. Mamadaliyeva, Abbaskhan S. Turaev

Formulation and evaluation of pellets of natural okra gum prepared by extrusion and spheronization
Hemant K S Yadav, Shahnaz Usman, K.V.R.N.S. Ramesh, Quamrul Islam

Efficacy of eel (Monopterus albus) extract gel and membrane on incision wound healing
Febriyenti, A. Almahdy, Riska Ropika Hasibuan

Cloning of acetoacetyl-coa reductase and polyhydroxybutyrate synthase genes from the local isolate Bacillus aryabhattai 6n-nrc into Escherichia coli
Neveen M. El-Metwally, Nasser A. Abd El-Khattab, Mona S. Shafei, Reda F. Allam, Yasser M. Ragab, Magdy A. Amin

Evaluation of antidiabetic, antidiarrheal and sedative effects of the methanolic extract of Clerodendrum viscosum roots in mice
Mohammed S. Rahman, Hasina Yasmin, Md. Harun Or Rashid, Nihad Adnan, Mohd. R. Jamiruddin, Md. Tanvir Kabir

Development and validation of the analytical method for the estimation of a combination of 5-fluorouracil and imiquimod by rp-hplc
Bhupender Tomar, Ankita Sharma, Inder Kumar, Sandeep Jain, Pallavi Ahirrao

Method development and validation for estimation of related substances in tilorone dihydrochloride using rp-hplc
M. Zeba Baktiyar, B. Mohammed Ishaq, Siva Sanker L Reddy, M. Sreenivasulu

Prediction model “t2dp” for the onset of type 2 diabetes mellitus
Muaed Jamal Alomar, Moawia M. Al-Tabakha, Zeinab Abdirizak Hussein

In-vitro cytotoxic and antioxidant activity of Bauhinia racemosa root
P. Aravanan, S. Jayakumari

In-vitro and In-vivo evaluation of anti-asthmatic activity of Eugenia jambolana bark
Prabha N. Bhong, Dr. Naikawade S. Nilofar, Mali R. Pratibha, Bindu S. Madhavi

Patients’ beliefs towards generic medicines in the united arab emirates
Imen Guella, Nageeb Hassan, Moyad Shahwan, Yaser Mohammed Al-Worafi, Sahab Alkhoujah

Validated stability indicating method for determination of indapamide in pharmaceutical formulation
Dr. Gopal Prasad Agrawal

F2-isoprostane levels in deoxycorticosterone acetate (doca)-salt induced hypertensive rats administered with coffee-corn mixture
Sugiyanta Sugiyanta, Harianto Notopuro, Jusak Nugraha, Retno Handajani

Comparison of 3-carbethoxy-4-phenyl-but-3-en-2-one and methylene quinuclidinone as a ligand to reactivate mutant p53: Molecular docking study in three types of crystal structure mutant p53: 2bim, 2jiy, and 2j21
Jeffry Julianus, Jumina, Mustofa

Simultaneous method development and validation by hplc for capecitabine and oxaliplatin in mucoadhesive microspheres containing capsules
Krishna Patel, Dipti Patel

Characterization and optimization of oral solid supersaturable self-emulsifying drug delivery system of cilostazol
Ali N. Wannas, Nidhal K. Maraie

Preparation and study biological activity of polybarbiturate linked tetrazole ring
Ali Jabbar Radhi, Dhurgham Qasim Shaheed, Mohammed Hamza Heriz, Zeyad Kadhim Oleiwi

Characterization of cross-linked chitosan by ionic and covalent crosslinking agents as wall material of red ginger oleoresin microcapsules
Jayanudin, Rochmadi, Moh. Fahrurrozi, Sang Kompiang Wirawan

Cytotoxic effect of Capsicum annum L. extract on T47D cells: In vitro study
Rochmah Kurnijasanti, Amaq Fadholly

Prevalence of pain and self-medication pattern of paracetamol and nsaids among university students in united arab emirates
Nageeb A.G.M. Hassan, Sabrina Ait Gacem, Afnan Abdul-Hameed Al-Qaysi, Maryam Jaafar Al-Aani

Assessment of zinc, iron, and microbes concentrations in blood cockles (Anadara granosa) as complementary foods and implications for reducing of micronutrition deficiency
Margaretha Solang, Djuna Lamondo, Ramli Utina, Syam Kumaji, Zuliyanto Zakaria

Review of the impact covid-19 has on the psychosocial factors affecting well-being
Sheila FBSCH Menon, Vidya Bhagat

Obesity and depression: Could some shared genes explain the relationship?
Nouran Yonis, Moustafa Sayed

Evaluation of pharmacological properties, phytochemistry and medicinal uses of Cissampelos owariensis
Alfred Maroyi

A comprehensive study on synthesis and biological activities of pyridazine derivatives
Aamir Malik, Rakhi Mishra, Rupa Mazumder, Avijit Mazumder, Prem Shankar Mishra

Lepadigathis cristata wild. traditional plant of chhattisgarh tribes: An alternative cure
Bharti Ahirwar, Dheeraj Ahirwar

Pulmonary aerosolized formulation or nasal drops containing recombinant human angiotensin converting enzyme 2 (rhace2) as a potential therapy against covid-19
Amjad Ayoub, Nishat Fatima, Vichitra Kaushik

Sars-cov-2 (covid-19) and role of real time reverse transcription polymerase chain reaction (rt-pcr) in its diagnosis
Pinki, Deepika Rani, Himani Bajaj, Ranjit Singh

An updated review of what, when and how of sertaconazole: A potent antifungal agent
Charanjit Kaur, Navjeet Kaur, Deepika Sharma, Gurvinder Singh, Narinderpal Singh, Viney, Sachin Kumar Singh, Vrinderpal Singh, Rajesh Kumar

Regulatory strategies for orphan drug development in usa-europe
D.M Ranjini, Sadiq G. Basha, N. Prabakaran

Tolvaptan in hyponatremia - a pharmacologic approach
Anna Paul, R. Lakshmi

Microspheres as therapeutically effective multiparticulate drug delivery system: A systemic review
Ashwin Kumar Saxena, Aditya Sharma, Navneet Verma

Clinical impact of combination therapy in diabetic neuropathy and nephropathy
Harmeet Kaur, Arvinder Kaur, Pankaj Kumar Prashar, Anamika Gautam, Ankita Sood, Sachin Kumar Singh, Monica Gulati, Narendra Kumar Pandey, Bimlesh Kumar

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