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Research Journal of Pharmacy and Technology
Year : 2021, Volume : 14, Issue : 5
First page : ( 2873) Last page : ( 2877)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2021.00505

Analytical methods for estimation of budesonide in bulk and in pharmaceutical dosage forms: A review

Kolsure Anuja1, Daniel Kratika2, Bhat Mahesh3

1Research Scholar, BRNCOP, Department of Pharmacy, Mandsaur University, Mandsaur, Madhya Pradesh, India

2BRNCOP, Department of Pharmacy, Mandsaur University, Mandsaur, Madhya Pradesh, India

3Department of Pharmaceutical Chemistry, Sant Gajanan Maharaj College of Pharmacy, Mahagaon, Kolhapur, Maharashtra, India

*Corresponding Author E-mail: anuja.kolsure63@gmail.com

Online published on 25 August, 2021.

Abstract

Budesonide is a potent glucocorticoid with a high local anti-inflammatory effect and low systemic bioavailability. The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease. Several analytical methods including UV, HPLC, LC-MS techniques has been developed for Budesonide alone and in combination with others. Methods indicating HPLC bioanalytical method, stability indicating HPLC method, ion pairing chromatographic method and chemometrics assisted HPLC methods are also described for Budesonide. For qualitative and quantitative estimation of Budesonide these analytical methods can be used. The following study describes reported analytical methods of Budesonide.

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Keywords

Budesonide, Formoterol fumarate, UV-Spectroscopy, RP-HPLC, LC-MS.

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