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Research Journal of Pharmacy and Technology
Year : 2021, Volume : 14, Issue : 5
First page : ( 2867) Last page : ( 2872)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2021.00504

Viridescent concoction of genstein tendentious silver nanoparticles for breast cancer

Singh Aditya1,*, Ansari Vaseem A.1, Ahsan Farogh1, Akhtar Juber1, Khushwaha Poonam1, Maheshwari Shubhrat2,*, Rufaida1

1Faculty of Pharmacy, Integral University, LucknowIndia

2Shri Ram Murti Smarak College of Engineering and Technology, Pharmacy Bareilly India

*Corresponding Author E-mail: vaseem@iul.ac.in

Online published on 25 August, 2021.

Abstract

Cancer predicament is a global concern because of the ability of swift growth to cause infection to the cell. Breast cancer is the fifth contemplative reason for cancer death many scientific approaches have been thriving to deal with it and to make anticancer agent, therapeutic, safe and effective. In this burgeon silver was found as antitumor agent with noteworthy properties of conductivity, stability, and activity. Soy isoflavones mainly derived from soybean have accure much attention as dietary components having inhibitory effects on breast cancer and prostate cancer in Asians, who consume 20–50 times more than Americans, soy diet act as a natural chemopreventive agent. Previous data show that nanoparticles of silver are effective against a wide spectrum of bacteria, fungi, viruses, some infectious diseases and burn wounds. Now genistein has been found to inhibit the growth of various cancer cell lines including prostate and breast cancer cells. Nanoparticles needed to be biosynthesized because of the expensive, physical and. chemical processes. Chemical synthesis also contributes to the appearance on the surface of some toxic chemical that can adversely affect medical applications. Green synthesis offers advances over chemical and physical method because it is price effective, environmentally friendly, easily scaled up for large scale synthesis and does not requires use high pressure, energy, temperature and toxic chemicals.

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Keywords

Breast Cancer, Antitumour, Genistein, Chemopreventive, Nanoparticles.

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