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Research Journal of Pharmacy and Technology
Year : 2021, Volume : 14, Issue : 5
First page : ( 2649) Last page : ( 2652)
Print ISSN : 0974-3618. Online ISSN : 0974-360X.
Article DOI : 10.52711/0974-360X.2021.00467

Comparative study of insecticide potential of methyl parathion and diazinon in Drosophila melanogaster

Sahoo Suman2, Acharyya Mausumi Ari3, Muniyan Rajiniraja1,*

1Department of Biotechnology, School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore - 632014

2Department of Biomedical Genetics, School of Bio Sciences and Technology, Vellore of Technology, Vellore - 632014

3Institute of Genetic Engineering, Kolkata - 700128

*Corresponding Author E-mail: rajiniraja.m@vit.ac.in

Online published on 25 August, 2021.

Abstract

Several reports indicate that many chemical pollutants which are widely spread in the environment, such as insecticide, pesticide and drugs are mutagenic in various test system. These findings reflect an urgent need to draw more attention to the possible genetic hazards of such pollutants to public health. The present investigation of working hypothesis deals with the effects of two insecticides viz. Methyl Parathion (MeP) and Diazinon (DZ) on non-target organism Drosophila melanogaster. We have carried out the chromosomal aberration test with various concentration for insecticides (MeP and DZ) which infer properties like ectopic pairing, inversion loop, puffing, fusion, and asynapsis. Chromosomal aberration result shows significant effects with DZ even in less concentration (0.02ppm) when compared with MeP (0.2ppm). The present study proposes that diazinon is more cytotoxic than methyl parathion in Drosophila melanogaster.

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Keywords

Chromosomal aberration test, Methyl Parathion, Diazinon.

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