Anthelmintic and Anti-Insect Activities of Memecylon umbellatum Burm Root Extracts Killedar SG*, More HN Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Kolhapur, Maharashtra, India *Corresponding Author: Mr. Suresh. G. Killedar Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Near Chitranagari, Kolhapur-416 013 (M.S.) India, Mobile No. 09890146006 E-mail: sureshgk_64@rediffmail.com
Online published on 20 March, 2013. Abstract Different extracts of Memecylon umbellatum Burm root were screened for Anthelmintic and anti-insect activities using Indian earthworms (Pheretima posthuma) and red flour beetle, Tribolium castaneum (Herbst) respectively. The acetone and methanolic extracts exhibited significant (p<0.01) anthelmintic and anti-insect activities compared with the control and other extracts. Albendazole and Piperazine citrate were used as standards for anthelmintic activity while Neem Extract, Celphos (Aluminium phosphide) and citronellal for anti-insect activity. Chloroform, ethyl acetate and aqueous extracts showed weak activities. Acetone root extract showed most promising Anthelmintic activity at 20mg/mi compare to albendazole and insecticidal activity at 10mg concentration comparable to standard celphos (5%). Further investigations are however necessary to explore mechanism(s) of action involved in these pharmacological activities and constituents responsible for both the activities. Top Keywords Memecylon umbellatum, Anthelmintic, anti-insect, Pheretima posthuma, Tribolium castaneum. Top |