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Research Journal of Pharmacology and Pharmacodynamics
Year : 2010, Volume : 2, Issue : 1
First page : ( 39) Last page : ( 41)
Print ISSN : 0975-4407.

A comparative Study on the Antidiabetic Effect of Nelumbo nucifera and Glimepiride in Streptozotocin Induced Diabetic Rats

Rakesh Poluru*, Panyala Srinivasa Reddy, Siddig Mahmoud, Ramadas C, Kumar KL Senthil, Sekar D Sathish

Padmavathi College of Pharmacy and Research Institute, Periyanahalli, Dharamapuri, Tamilnadu-635 205

*Corresponding Author: Dr. K. L. Senthilkumar, Principal, Padmavathi College of Pharmacy and Research Institute, Dharmapuri, Tamilnadu. E.mail: kames.vel@gmail.com.

Online published on 20 March, 2013.

Abstract

The present study is aimed to evaluate the anti diabetic effect of Nelumbo nucifera rhizome and flower extracts on serum glucose level in normal and streptozotocin induced diabetic rats. The various extracts was prepared and screened for their effects on serum glucose level in rats. In streptozotocin induced animals the various extracts showed significant anti diabetic property. From the result of these studies, we can conclude that the Nelumbo nucifera rhizome and flower extract is a promising anti diabetic agent.

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Keywords

Nelumbo nucifera, anti diabetic activity, streptozotocin induced diabetic rats.

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