Preliminary Phytochemical Screening and Antioxidant Activity of Petroleum Ether Extract of Trichosanthes dioica Roxb (Fruits) Shivhare Yogesh*, Singh Priya, Patel K. K., Soni Prashant Department of Pharmacognosy, VNS Institute of Pharmacy, Bhopal (M.P.) *Corresponding Author: Mr. Yogesh Shivhare Lecturer Postal address: 30, Gomati colony Nehru Nagar, Bhopal (M.P.) India E-mail ID: yogesh_aot@rediffmail.com, Mobile No. 09926225738
Online published on 21 March, 2013. Abstract In-vitro antioxidant activity of petroleum ether extract of Trichosanthes dioica was determined by DPPH free radical scavenging assay, Reducing power assay, Nitric oxide scavenging activity, Hydrogen peroxide radical scavenging activity using ascorbic acid as a standard. The IC50 values were calculated for all the models in order to evaluate the antioxidant efficiency of Trichosanthes dioica extract. In all the testing a significant correlation existed between concentration of the extract and % inhibition of free radicals. Obtained results clearly indicated that petroleum ether extract of Trichosanthes dioica possesses significant antioxidant potential as compared with standard. Top Keywords Trichosanthes dioica, Nitric oxide, % Inhibition. Top |