Antihyperglycemic Activity of Strychnos potatorum Seed and Leaf Methanolic Extracts in Alloxan-Induced Diabetic Rats Raju T Pandu1,*, Shastri KJR2, Reddy C Srinivas1, Reddy VM1 1Department of Pharmacognosy, Vaagdevi College of Pharmacy, Hanumakonda, Warangal, Andhra Pradesh, India 2Department of Ayurvedic, Ananthalaxmi Ayurvedic Government Medical College, Warangal, Andhra Pradesh, India *Corresponding Author: T. Pandu Raju, Vaagdevi College of Pharmacy, Kishanpura, Hanumakonda, Warangal – 506001, (AP). Mobile: + 91 9492439636, 9000796969. E-mail: pandurajrx100@yahoo.co.in
Online published on 21 March, 2013. Abstract The pharmacognostic and phytochemical examinations of different solvents extracts of seeds and leaves of Strychnos potatorum were conducted and their antidiabetic activity was evaluated.The administration of methanolic extracts of seeds and leaves of Strychnos potatorum by oral route at doses; 200 and 400 mg/kg b.w. at every 3 hour interval reduced blood glucose levels by24.23%, 25.67%, 16.47% and 17.88%, respectively in alloxan-induced diabetic rats. Top Keywords Strychnos potatorum, Alloxan, antihyperglycemic activity, Loganiaceae, MESP (methanolic extract of seed Powder), MELP (methanolic extract of leaf powder). Top |