Metastatic cholangiocellular carcinoma in Kankrej bullock Raval S.H.2,*, Joshi D.V.1,2, Erin Ball1,2, Bruce Williams2, Patel B.J.2, Patel J.G.2, Parmar S.N.2 2Department of veterinary Pathology, College of Veterinary Science and A.H.Sardarkrushinagar Dantiwada Agricultural University (SDAU), Sardarkrushinagar, Gujarat 1Joint Pathology Center, Silver Spring, MD, USA *Corresponding author: e-mail: samirraval81@gmail.com
Abstract Sixteen years old castrated Kankrej male was found dead after short clinical illness. On necropsy, multiple yellow to yellowish white, umbilicated, well demarcated, firm nodules of 3 to 20 cm in size were found on liver, lung, adrenals, lymph nodes and thoracic wall. Histologically, neoplasm was composed of round to polygonal cells arranged in irregular mass, poorly formed ducts, supported by a moderate to dense collagenous fibrovascular stroma.Neoplasm was diagnosed as poorly differentiated cholangiocellular carcinoma with desmoplasia. Diagnosis was confirmed by positive cytokeratin 7/17 immunostaining. Top Keywords Cholangiocellular carcinoma, Immunohistochemistry, Kankrej cattle, Metastasis. Top |