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Pathology of epidermoid cyst in the spinal cord of swiss albino mice Prasad M.C.1,*, Brahmankar M.G.1, Kapurkar U.M.1, Adak A.1, Lonkar P.S.1, Patel M.V.1, Pavitrakar Vishal1, Bokan Sanjay1, Sharma Sharad1 1Pathology Section Department of Toxicology, Jai Research Foundation, Vapi-396195, Gujarat, India *Corresponding author: email: pathology@jrfonline.com
Abstract Two cases of epidermoid cyst were recorded one each in male and female Swiss albino mice (3–4 months) out of about 2000 mice used in various toxicity studies. These were located in the white matter of lumber segment of spinal cord. No clinical sign during life phase and gross lesion on necropsy were recorded. Histopathological features consisted of multilayered stratified squamous epithelial cystic wall having either keratinaceous debris or concentric laminated layers of keratin in the lumen. It was considered to be an incidental finding of congenital origin. Top Keywords Epidermoid cyst, Histopathology, Mice, Spinal cord. Top | ACKNOWLEDGEMENTS Authors are thankful to the Management of Jai Research Foundation, Vapi and Lupin, pharmaceuticals, Pune for extending the facilities and grant of permission to publish the findings. |
Top Figures Fig. 1.: Irregularly oval epidermoid cyst embedded in white matter and lined by stratified squamous epithelium containing desquamated keratin in lumen. H&E ×100;
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| Fig. 2.: Irregularly oval epidermoid cyst embedded in white matter and lined by stratified squamous epithelium containing concentric layers of desquamated keratin in lumen. H&E ×100.
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