Clinicopathological assessment of cutaneous multicentric lymphoma in a dog Madheswaran R.2,1, Sivaseelan S.2, Ponnusamy K.K.2,1, Balasubramaniam G.A.2, Arulmozhi A.2, Balachandran P.2 2Department of Veterinary Pathology, Veterinary College and Research Institute, Namakkal-637 002, Tamil Nadu, India 1department of Veterinary Clinical Medicine, Ethics and Jurisprudence, Veterinary College and Research Institute, Namakkal-637 002, Tamil Nadu, India *Corresponding author: email: rmadheswaran2003@gmail.com
Abstract A case of cutaneous multicentric lymphoma was observed in a 2-year-old male mongrel dog. The dog was brought to the small animal clinic with the history of anorexia and vomiting. Clinical examination of the dog revealed no abnormality except generalized lymphadenopathy. Haematological parameters revealed altered blood pictures and significantly elevated leucocyte count due to neutrophilia. Serum biochemistry parameters did not reveal any abnormality. Microscopical examination of fine needle aspiration smears revealed predominantly lymphoblasts and few lymphocytes. Cytoplasm of the neoplastic cells were bluish in colour, granular in appearance and had numerous vacuoles and fragments. Nuclei were round to oval, occasionally elliptical and often irregular in shape with numerous mitotic figures. Histologically, abundant cell population consisting of mature lymphocytes and few lymphoblasts were observed. Neoplastic cells were round with moderate cytoplasm. Nuclei were spherical and hyperchromatic with prominent central nucleoli. Cytology and histopathology findings were consistent with the diagnosis of canine cutaneous multicentric lymphoma. Top Keywords Canine lymphoma, Cytology, Haemato-biochemistry, Histopathology. Top |