Year : 2011, Volume : 35, Issue : 2
First page : ( 209) Last page : ( 210)
Print ISSN : 0250-4758. Online ISSN : 0973-970X. Published online : 2011 December 1.

Papillary cystic cholangio cellular carcinoma in a dog with metastasis in the bronchial lymph node

Pramod S.^*,2, Nair N.D.², Anju A.J.^1,2, Ali Ashny², Vijayan N.², Lalithakunjamma C.R.²

²Department of Veterinary Pathology, College of Veterinary and Animal Sciences, Kerala Veterinary and Animal Sciences University (KVASU), Mannuthy, Thrissur, 680651, Kerala

¹department of Veterinary Clinical Medicine, College of Veterinary and Animal Sciences, Kerala Veterinary and Animal Sciences University (KVASU), Mannuthy, Thrissur, 680651, Kerala

*Corresponding author: email: spramodvet@gmail.com, Mobile: 09447749837

Received:  03  August,  2011; Accepted:  19  October,  2011.

Abstract

Papillary cystic cholangio cellular carcinoma encountered in a dog appeared as firm, white and nodular mass in general except for cystic dilatation in some areas. Bronchial lymph node was enlarged to the extent, that it was pressing and constricting the posterior trachea. Histopathologically, well differentiated glandular structures lined by the neoplastic columnar cells resembling normal biliary epithelium were noticed. The stromal reaction was marked. The metastasis in the bronchial lymph node resembled the primary hepatic lesion.

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Keywords

Cholangio cellular carcinoma, Dog, Lymph node, Metastasis.

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Figures

Fig. 1.: Gross photograph of liver showing white, irregular, nodular tumor mass replacing the proximal half of the left lateral lobe. TopBack

Fig. 2.: Liver section showing well formed glandular structures lined by pleomorphic cuboidal and columnar cells resembling normal biliary epithelium with various degrees of hyperchromasia and mitoses. H&E *100. TopBack

Fig. 3.: Liver section showing proliferation of the neoplastic ductular epithelium forming papillary projections and filling the entire tubular lumen. H&E *100. TopBack

Fig. 4.: Lymph node section showing metastasis with proliferating cystic glandular structure lined by hyperplastic epithelium forming papillary projections. H&E *100. TopBack