Epidemio-pathological studies of gout in broiler birds in West Bengal Jana S.1,2, Mukhopadhayay S.K.*,2, Niyogi D.2, Singh Y. Damodar2, Thiyagaseelan C.2 2Department of Veterinary Pathology, West Bengal University of Animal and Fishery Sciences, 68, K. B. Sarani, Belgachia, Kolkata-700 037, India 1Suven Life Sciences Ltd., Discovery Toxicology IDA, Jeebimepla, Hyaderabad-500 055 *Corresponding author: e-mail:skmpath@gmail.com.
Abstract A total of 33,713 broiler birds were examined during 2004 and 2005 in West Bengal to study the incidence andpathology of gout. Overall, 7.03% incidence of gout was recorded. Clinically, the affected birds showed dullness unthriftiness, reduced feed intake, loss of body weight, diarrhoea and death. Grossly, gouty birds revealed chalky white urate deposition in the subcutaneous as well as in the visceral organs tissues. Microscopically, kidneys exhibited excessive deposition of urate crystals in the glomeruli and tubules. Liver had congestion and haemorrhages with occasional urate deposition. Heart and lungs revealed vascular changes along with urate deposition and cellular infiltration. Spleen had congestion, haemorrhages and depletion of lymphoidal cells. Intestine showed necrosis of mucosa with exfoliation in the lumen. The synovial membrane of the joint was swollen, hyperemic with inflammatory cell infiltration. Urate crystals in the periarticular tissues were found. Kidney sections stained with De Galantha's method revealed black, needle shaped urate crystals arranged in a radiating manner. Top Keywords Broiler birds, Histochemical changes, Gout, Pathomorphology. Top |