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Year : 2009, Volume : 33, Issue : 1
First page : ( 69) Last page : ( 72)
Print ISSN : 0250-4758. Online ISSN : 0973-970X. Published online : 2009 June 1.

Comparison of capture-ELISA with cultural isolation for detection of Mycoplasma mycoides subsp. mycoides (LC type, M-30) in experimentally infected lambs

Dahiya S.K.1, Tiwari S.C.1, Batra Munish2,*, Sharma Alok3

1Department of Veterinary Microbiology, College of Veterinary Sciences, CCS Haryana Agricultural University, Hisar-125 004. India.

2Department of Veterinary Pathology, CVASc, GBPUAT, Pantnagar.

3Department of Veterinary and Animal Husbandry Extension, CSKHPKV, Palampur.

†Corresponding author.

Abstract

A capture-ELISA was standardized in order to avoid the time consuming and comparatively less sensitive cultural reisolation for detection of Mycoplasma mycoides subsp. mycoides (LC, M-30) [MmmLC] in the tissues of experimentally infected lambs and compared with results of reisolation of MmmLC. The organism could be recovered from 65.55% of the specimens examined for cultural reisolation. Capture-ELISA detected MmmLC antigens in 73.33% of the examined tissues. Comparison of results of both the techniques revealed a 90% agreement and 10% disagreement. It was concluded from the present studies that capture-ELISA is a more sensitive technique than reisolation of organism for detection of MmmLC in the tissues of the animals.

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Keywords

Culture, ELISA, Lambs, M. mycoides subsp. mycoides.

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