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International Journal of Medical Research & Health Sciences
Year : 2020, Volume : 9, Issue : 4
First page : ( 61) Last page : ( 66)
Online ISSN : 2319-5886.

To determine the frequency of successful outcome of multi-drug resistant tuberculosis treated as outpatient in a tertiary care center

Pervez Naveed1, Haq Zia Ul2, Khan Imtiaz3, Umar Muhammad4,*

1Department of Pulmonology, Lady Reading Hospital, Peshawar, Pakistan

2Department of Pulmonology, Gajju Khan Medical College, Swabi, Pakistan

3Gajju Khan Medical College, Swabi, Pakistan

4Department of Pulmonology, Lady Reading Hospital, Peshawar, Pakistan

*Corresponding e-mail: drumar98@gmail.com

Online published on 1 October, 2020.

Abstract

Objectives

To determine the frequency of successful outcome of multidrug-resistant tuberculosis treated as outpatient in a tertiary care center.

Subject and Methods

This was a descriptive cross-sectional study done from 13 April, 2018 to 13 Oct, 2018. All the patients fulfilling inclusion criteria having age 20-60 years of either gender under treatment-of MDR-TB for more than six months were enrolled in study the from Programmatic Management of Drug Resistance Tuberculosis (PMDT) site at Department of Pulmonology. Informed consent was taken from patients. Strictly exclusion criteria i.e. patients having neurological or psychological problems before diagnoses of MDR-TB (as per medical record in history), co-infection with HIV, was followed to exclude potential confounder and biases. Education status was evaluated and the response of treatment was checked in matriculate & under matric patients, also socioeconomic status was evaluated by asking about monthly salary whether below or above 12000, and subsequently their effect on treatment outcome. HIV screening is done through ICT method and DST for tuberculosis done on sputum of the patients in the Provincial Reference Lab in Hayat Abad Medical Complex Peshawar for diagnosis.

Results

A total of 151 patients were included in this study, among which males were 94, and females were 57. The mean age was 41 years and S.D 10.82. As per the results, 110 (72.84%) patients were having a successful outcome.

Conclusion

This study concludes that the out-patient treatment strategy success rate was 72.84% and it is feasible and safe for the treatment of MDR-TB patients.

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Keywords

Tuberculosis (TB), Programmatic management of drug resistance tuberculosis (PMDT), Multidrugresistant (MDR) strains.

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