Evaluate Some Biochemical Variables of Obese Iraqi Children in Baghdad City Jwaid Shatha H. M. Sc. Lecturer, Middle Technical University, Iraq, Collage of Health &Medical Technology, Baghdad Online published on 27 November, 2019. Abstract Obesity in children is a medical problem that can affect their health in the future. These include serious cases such as type 2 diabetes, high cholesterol, high blood pressure-previously seen as adult diseases and many endocrine abnormalities including” thyroid dysfunction” The study carried out at the pediatrics department, Baghdad hospital. Total (70) subjects selected from the coming patients and(30)healthy children. Age in each groups between (5month-10 years). The aimed of this study assess the alteration in some sera levels of biochemical parameters (TSH, T3, T4, ALT, AST, ALP) with body mass index in obese child and compare the result with some parameters of non-obese children in Baghdad city. Thyroid function tests (TSH, T3, and T4) were measured in all subjects in both groups using enzyme linked fluorescent method to screening for thyroid dysfunctions. Liverenzymes test (ALT, AST, ALP) was determined by colorimetric method. Results show that the majority of obese children (42.8%) are aged in (6–10 years). This study statistically showed increased level of TSH among obese children compare with healthy control with a highly significant increase between them (p< 0.0001), while the levels of T3, T4 showed no influence on obese children (p>0.05). There was no significant increase in serum (AST, ALT, ALP) in this study in obesity children and healthy children(p>0.05). Increased weight in children may be caused by the main imbalance in the thyroid hormones especially thyroid stimulating hormone (TSH). “Hypothyroidism” in obese children when left untreated may lead to uncontrollable diseases such as mental retardation. Thyroid hormones should be examined in obese children regularly to check for any effects that lead to diseases that are difficult to control. Top Keywords Body mass index (BMI), thyroxin (T4), thyroid-stimulating hormone (TSH), triiodothyrionine (T3) aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (Alp). Top |