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Indian Journal of Forensic Medicine & Toxicology
Year : 2019, Volume : 13, Issue : 4
First page : ( 799) Last page : ( 803)
Print ISSN : 0973-9122. Online ISSN : 0973-9130.
Article DOI : 10.5958/0973-9130.2019.00392.X

Estimation of serum levels of some immunological and Heamatological changes in patient infected with Salmonella bacteria in Sammara city, Iraq

Majeed Moazaz Abd Alrida1, Armeet Huda Shafeek1, Fadhil Khansaa Basem2

1Dep. Techniques of Healthy Nutrition, Institute of Medical Technology Baghdad Middle Technical University, Iraq

2Dep. of Pathological Analysis, AL-Dour Technical Institute, Northern Technical University

Online published on 27 November, 2019.

Abstract

Background

For a long period, Salmonella infections are responsible for gastroenteritis outbreaks in developed nations and typhoid fever and nontyphoidal Salmonella bacteremia in developing nations. Typhoid is caused by Salmonella infection and has been detected in the Hospital and Health Center in Sammara city. The aim of current study was to investigate the correlation between some of immunological biomarkers (C3, C4) and hematological changes in patients infected with Salmonella bacteria in Sammara city, Iraq.

Method

Samples obtained from participants were cultured on Nutrient agar plate. Identification of Salmonella infection was performed by using the VITEK 2 automatic system.

Also, different cultural, bio-chemical, serological and molecular studies were used to characterize Salmonella organisms.

Results and Conclusions

Data showed that out of 50 samples included, 25 were positive for Salmonella infection, while 25 samples were negative for Salmonella infection (The control group included 25 clinically healthy children without Salmonella infection matched for age and sex with pateints). The results obtained in present study showed that there was no significant difference in the level of PCV, RBCs and Hb with significantly higher (P<0.05) in typhoid patient compared to the apparently healthy control individuals. Also, that there was no significant decrease in WBC (P<0.05) when compared with the apparently healthy control individuals. The moderate increase in lymphocytes in apparently healthy individuals could be linked to environmental factors and also there was no significant effect on basophiles count.

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Keywords

Typoid fever, immunological biomarkers, Hematological indices, Salmonella bacteria, serological tests.

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