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International Journal of Drug Regulatory Affairs (IJDRA)
Year : 2018, Volume : 6, Issue : 1
First page : ( 1) Last page : ( 7)
Print ISSN : 2321-2162. Online ISSN : 2321-6794.
Article DOI : 10.22270/ijdra.v6i1.220

An overview about novel fast dissolving oral films

Sharma Pravin Kumar1,*, Sharma Pankaj Kumar1, Darwhekar Gajanan N.2, Shrivastava Birendra1

1School of Pharmaceutical Sciences, Jaipur National University, Jaipur (Rajasthan) India

2Acropolis Institute of Pharmaceutical Education and Research, Indore (MP) India

*Corresponding Author's E-mail: praveensharma910@gmail.com

Online published on 17 September, 2019.

Abstract

Nowadays, novel fast dissolving oral films (FDF) have come in existence as an alternative dosage form in comparison with tablet, capsules, syrup and other oral dosage forms with respect to patient convenience and compliance. Fast dissolving oral films are helpful to paediatric and geriatric patients who experience difficulties in swallowing traditional oral solid-dosage forms. The FDF drug delivery systems are solid dosage form which disintegrate or dissolve within seconds when placed in the mouth cavity without need of water or chewing. FDF provide better drug dissolution, faster onset of action, bypassing the first pass metabolism of drugs and thus enhance their oral bioavailability with reduced dosing frequency. These formulations are suitable for cough, cold, sore throat, allergenic conditions, nausea, pain, hypertension and CNS disorders. The present review provides the details about the recent advancement in design and development of oral fast dissolving film.

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Keywords

Fast dissolving oral film, Bioavailability, Solvent casting technique, Plasticizer.

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