Clinicopathological studies on spontaneous Cysticercus fasciolaris infection in wild and laboratory rats Goswami R., Singh S.M., Kataria M.1, Somvanshi R.* Department of Animal Sciences, M.J.P. Rohilkhand University, Bareilly, (Uttar Pradesh) 1Division of Biochemistry, Indian Veterinary Research Institute, Izatnagar-243122 ** Corresponding author: Division of Pathology, Indian Veterinary Research Institute, Izatnagar-243122; dr.rsomvanshi@gmail.comsomvanshi@ivri.res.in
Abstract The spontaneous prevalence of Cysticercus fasciolaris, intermediate stage of cat tapeworm, Taenia taeniformis infection was diagnosed as 16.66% in rats at Bareilly, Uttar Pradesh. It was higher in laboratory rats than wild rats. C. fasciolaris caused sub-clinical infection without causing mortality. Its single cyst induced significant alterations in serum protein and enzyme (albumin, ALP and SGOT) values causing hepatic damage in CfWR's than CWR's. Tissue enzymes in liver, stomach and intestine showed significant increased LP, catalase, AChE values while GSH and SDH values were decreased in these organs. On necropsy, liver revealed mild infection of C. fasciolaris. Histopathologically, liver showed C. fasciolaris cyst which was characterized by presence of parasitic larva in its lumina. Parasitic cystic wall was thick, comprised of multiple connective tissue layers. In adjoining areas engorged blood vessels, pressure atrophy of hepatic cells, mononuclear cellular infiltration and occasionally presence of bluish colored mast-like cells were seen. Infrequently engorged hepatic sinusoids and blood vessels, biliary duct hyperplasia and mononuclear cellular infiltration in portal triad were also observed. From present study, it was concluded that even single cyst infection of C. fasciolaris may mislead results of liver function in rats. Top |