Synthesis, Characterization and Antimicrobial Screening of Some Novel Chromonyl Chalcones Sharma V.P.1, Kumar Rakesh2,* 1Department of Chemistry, Meerut College, Meerut (UP) India 2Department of Chemistry, M.M.M. (P.G.) College, Bhatpar Rani, Deoria (UP) India, 274702 *Corresponding Author E-mail: rakesh01071981@gmail.com
Online published on 28 August, 2014. Abstract Synthesis of some novel 6-acetyl-2-aryl/furyl chromones [4(a-b)] by Friedal-Craft's acylation of 2-aryl/furyl chromones [3(a-b)] and 1-(2’-aryl/furyl chromon-6’-yl)-3-aryl or heteroarylprop-2-en-1-ones [5(a-f)] by Claisen-Schmidt condensation is being reported in this publication. The synthesized compounds have been characterized by elemental analysis, FT-IR and PMR spectral data. The synthesized compounds have been evaluated for their antibacterial and antifungal activities. Most of the compounds have been found moderately active when compared with the reference standard drugs. Top Keywords Chromones, Chalcones, Friedal-Craft's acylation, Claisen-Schmidt condensation, antifungal and antibacterial activity. Top |