Synthesis of Some New 3-(4-Phthalimidophenyl)-5-(Substituted Phenyl) 4-Isoxazoline Derivatives with Analgesic and Anti-Inflammatory Activities. Lande Deepak*, Deodhar Meenakshi, Bhosle Ashok, Bhawal Ganesh Dep. of Pharmaceutical Chemistry, SGRS College of Pharmacy, Saswad, Pune, Maharashtra-412301, India *Corresponding Author E-mail: deepak_lande@rediffmail.com
Online published on 6 March, 2013. Abstract The derivatives of 3-(4-phthalimidophenyl)-5-(substituted-phenyl)-4-isoxazoline were synthesized, which were screened for their analgesic and anti-inflammatory activity in test animals. The analgesic activity of all compounds were found to be higher than their anti-inflammatory activity, Compounds 3b, 3e, 3h and 3l were found to be more active among the synthesized compounds. Top Keywords Thalidomide, Isoxazoline, Anti-inflammatory, Hydroxylamine hydrochloride. Top |