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Asian Journal of Research in Chemistry
Year : 2011, Volume : 4, Issue : 2
First page : ( 244) Last page : ( 245)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.

Assay of Tolperisone by Extractive Spectrophotometry

Raghavi K.*, Shaiba M., Jagathi V., Sindhura M., Prashanthi R.

K.V. S. R. Siddhartha College of Pharmaceutical Sciences, Vijayawada-520010, Andhra Pradesh, India

*Corresponding Author E-mail: msindhu44@gmail.com

Online published on 6 March, 2013.

Abstract

Two simple and sensitive visible spectrophotometric methods have been developed for the estimation of Tolperisone in pure and pharmaceutical dosage forms. Method A is based on co-ordinate complex formation between the drug and cobalt thiocynate (630 nm) and method B is based on charge transfer complex formation between drug and 2,3 di-chloro-5-6-dicyano 1–4,benzoquinone (DDQ 430 nm). The absorbance are measured against the corresponding reagent blanks. The methods have been statistically evaluated and found to be precise and accurate.

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Keywords

Spectrophotometry, Tolperisone.

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