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Asian Journal of Research in Chemistry
Year : 2011, Volume : 4, Issue : 2
First page : ( 191) Last page : ( 194)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.

Green Synthesis of Nitrone and Isoxazolidines: A Convenient Method of Synthesis in Water

Chakraborty Bhaskar*, Rai Neelam, Chhetri Manjit S., Sharma Prawin K.

Organic Chemistry Laboratory, Sikkim Government College, Gangtok, Sikkim- 737102, India

*Corresponding Author E-mail: bhaskargtk@yahoo.com

Online published on 6 March, 2013.

Abstract

Novel C,N-diphenyl-α-amino nitrone has been synthesized in water and 1,3 dipolar cycloaddition reaction of the nitrone has been studied with maleimides in water. Significant rate acceleration and high yield of these reactions are observed in water compared with organic solvents. The structures of all the compounds have been established on the basis of spectral and analytical data.

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Keywords

C,N-diphenyl-α-amino nitrone, cycloaddition reaction, aqueous phase.

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