Synthesis, Characterization and Anti-Microbial Evaluation of Derivative of Chalcone Gopi C.*, Dhanaraju M. D. Research Lab, GIET School of Pharmacy, NH-5, Chaitanya Nagar, Rajahmundry-533294, India *Corresponding Author E-mail: gopi.baid@yahoo.com
Online published on 6 March, 2013. Abstract To development of antimicrobial agents a series of chalcones were prepared by condensation of appropriate acetophenones with different aromatic aldehyde in the presence of alkali at 37°C. The synthesized compounds were characterized by IR, NMR spectral studies. The synthesized compounds were evaluated for anti-bacterial activity, and anti-fungal activity. The result had shown that anti-bacterial and anti-fungal activity of Compound containing electron withdrawing group (G2, G4, and G6). Top Keywords chalcone, Aromatic aldehyde, acetophenone, anti-bacterial, anti-fungal. Top |