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Asian Journal of Research in Chemistry
Year : 2011, Volume : 4, Issue : 2
First page : ( 181) Last page : ( 182)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.

Synthesis, Characterization and Anti-Microbial Evaluation of Derivative of Chalcone

Gopi C.*, Dhanaraju M. D.

Research Lab, GIET School of Pharmacy, NH-5, Chaitanya Nagar, Rajahmundry-533294, India

*Corresponding Author E-mail: gopi.baid@yahoo.com

Online published on 6 March, 2013.

Abstract

To development of antimicrobial agents a series of chalcones were prepared by condensation of appropriate acetophenones with different aromatic aldehyde in the presence of alkali at 37°C. The synthesized compounds were characterized by IR, NMR spectral studies. The synthesized compounds were evaluated for anti-bacterial activity, and anti-fungal activity. The result had shown that anti-bacterial and anti-fungal activity of Compound containing electron withdrawing group (G2, G4, and G6).

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Keywords

chalcone, Aromatic aldehyde, acetophenone, anti-bacterial, anti-fungal.

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