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Asian Journal of Research in Chemistry
Year : 2011, Volume : 4, Issue : 1
First page : ( 64) Last page : ( 67)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.

Synthesis and Biological Evaluation of Some Novel Pyrimidine Derivatives

Divekar Kalpana*, Hardik Jani, Priyadarshini S. Brahmani

Department of Pharmaceutical Chemistry and Pharmaceutics, Dayananda Sagar College of Pharmacy. Kumaraswamy Layout, Bangalore – 560078. Karnataka State

*Corresponding Author E-mail: jani_goldberg@yahoo.com

Online published on 6 March, 2013.

Abstract

Pyrimidines are the class of heterocyclic compounds of pharmaceutical importance. The compounds having pyrimidine ring moiety are associated with fungicidal, anti-inflammatory, anti-HIV, antioxidant and anti-tumor activities. In the present study, an attempt was made to synthesize and characterize substituted pyrimidine derivatives and they were screened for antimicrobial and antioxidant activities by Filter disc method and DPPH method, respectively.

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Keywords

Pyrimidine, Antimicrobial activity, Antioxidant activity, Filter disc method.

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